ABSTRACT
Objective@#To explore the effect of air pollutants on salivary lysozyme of pupils in Hangzhou,and to provide a reference for effectively improving health index of primary school students.@*Methods@#A total of 248 healthy pupils from one primary school in Xiacheng district, Xihu district and Chun’an county of Hangzhou were selected with cluster random sampling methods during October 2015 to March 2016. Meteorological and air quality data near the three schools during the same period were collected. Mixed linear model was used to analyze the influence of air pollutants on salivary lysozyme of pupils.@*Results@#There was significant difference in the content of salivary enzymes between Xihu District and Xiacheng District (t=-4.49, 2.75, P<0.01). There was no significant difference in salivary lysozyme among pupils of different sex and age. Mixed linear model suggested that for 1 μg/m3 increase of PM2.5, PM10, SO2, NO2 and CO, salivary lysozyme increased by 1.75, 0.82, 6.12, 1.05 and 70.73 μg/L,respectively. Salivary lysozyme increased by 8.17 μg/L for 1 μg/m3 increase of SO2 the day before the test.@*Conclusion@#The level of salivary lysozyme in pupils is positively correlated with the concentration of air pollutants with a lagging effect.